Chung, KM, Hernandez, N, Sproul, A and WH Yu. Alzheimer’s disease and the autophagic-lysosomal system. Neurosc Lett (2019, Apr); 697(1): 49-58. PMID: 29758300 https://www.sciencedirect.com/science/article/abs/pii/S0304394018303446
Boland, B*, Yu, WH* …. MJ Millan. Clearing neurotoxic proteins in neurodegenerative disorders of aging. Nature Reviews in Drug Discovery (2018, Sep);17(9):660-688. PMID:30116051. *Equal contribution
Friedman, L.G., Qureshi, Y.H. and W. H. Yu. Promoting autophagic clearance: viable therapeutic targets in Alzheimer’s disease. Neurotherapeutics (2015, Jan); 12(1):1-15). PMID: 25421002 PMCID: PMC4322072 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322072/
Lee, J-H*, Yu, WH*, Kumar, A, Lee, SY, Mohan, PS, Peterhoff, CM, Wolfe, DM, Martinez-Vicente, Massey, AC, Sovak, G, Uchiyama, Y, Westaway, D, Cuervo, AM and RA Nixon. Presenilin 1 (PS1) is required for v-ATPase targeting and autolysosome acidification: PS1 mutations in Alzheimer’s Disease disrupt lysosomal proteolysis and autophagy. Cell (2010, Jun 25); 141(7):1146-58. PMID: 20541250. *equal contribution
Yu, WH, Cuervo, AM, Kumar, A, Peterhoff, CM, Boland, B, Schmidt, SD, Lee, JH, Mohan, PS, Mercken, M, Farmery, MR, Tjernberg, L, Jiang, Y, Duff, KD, Uchiyama, Y, Näslund, J, Mathews, PM, Cataldo, AM and RA Nixon. Macroautophagy – A novel amyloid-β (Aβ) peptide-generating pathway activated in Alzheimer’s disease. J Cell Biol (2005, Oct 10); 170(7):87-98. PMID: 16203860.
Nixon, RA, Weigel, J, Kumar, A, Yu, WH, Peterhoff, CM, Cataldo, AM, and Cuervo, AM Autophagy in the neurodegeneration of Alzheimer’s disease. J Neuropath and Experimental Neurol (2005, Feb); 64(2):113-2. PMID: 15751225.